Four were arrested including three teens after breaking into the Family Dollar at East 105th Street and St. Clair Avenue, police reported.
The store was a victim of a smash and grab on Saturday where suspects backed a vehicle through the front of the store.
According to Cleveland police, early on Wednesday they were called to the store again and found the back door open.
An adult and three kids, including two 14 year olds, were arrested at the scene.
Police said they used crowbars to get through the back door. Once the suspects had the store open they used an abandoned home next door to hide stolen merchandise.
Police at the scene said the suspects made several trips back and forth, each time taking hand fulls of stolen goods from the store.
The front of the building still shows the scars from Saturday's robbery with a large section boarded up with plywood.